Balancing hormones is crucial to a woman who is trying to become pregnant.  Progesterone prepares the uterine wall for implantation of the fertilized egg, without sufficient progesterone, the egg will be expelled. Progesterone treatment can also be used to induce fertility when there appears to be ovulatory dysfunction. A study was performed involving fifty women who had lived with infertility for a minimum of one-and-a-half years. Seventy percent of the women conceived within six months while exclusively using natural progesterone therapy. This group is described by “The Efficacy of Natural Progesterone in Achieving Successful Pregnancy”.

Five patients had a history of previous spontaneous abortions; all others had primary infertility. The range of ages was 18 to 39, with an average of 31. Their average period of infertility was 2.8 years in the 35 patients who conceived, and 2.7 years for the entire group.

The data from this study suggests that natural progesterone therapy offers very little risks to the patient and will be likely to benefit those wishing to conceive. Additional reports indicate that without natural progesterone treatment, women with luteal phase defect are at very high risk for spontaneous abortion. Progesterone has also been found to be important in maintaining a pregnancy during the first two trimesters.